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STRUM: structure-based prediction of protein stability changes upon single-point mutation

Motivation: Mutations in human genome are mainly through single nucleotide polymorphism, some of which can affect stability and function of proteins, causing human diseases. Several methods have been proposed to predict the effect of mutations on protein stability; but most require features from exp...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Quan, Lijun, Lv, Qiang, Zhang, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039926/
https://ncbi.nlm.nih.gov/pubmed/27318206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw361
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