Embryonic type Na(+) channel β-subunit, SCN3B masks the disease phenotype of Brugada syndrome

SCN5A is abundant in heart and has a major role in I(Na). Loss-of-function mutation in SCN5A results in Brugada syndrome (BrS), which causes sudden death in adults. It remains unclear why disease phenotype does not manifest in the young even though mutated SCN5A is expressed in the young. The aim of...

全面介紹

Na minha lista:
書目詳細資料
發表在:Sci Rep
Main Authors: Okata, Shinichiro, Yuasa, Shinsuke, Suzuki, Tomoyuki, Ito, Shogo, Makita, Naomasa, Yoshida, Tetsu, Li, Min, Kurokawa, Junko, Seki, Tomohisa, Egashira, Toru, Aizawa, Yoshiyasu, Kodaira, Masaki, Motoda, Chikaaki, Yozu, Gakuto, Shimojima, Masaya, Hayashiji, Nozomi, Hashimoto, Hisayuki, Kuroda, Yusuke, Tanaka, Atsushi, Murata, Mitsushige, Aiba, Takeshi, Shimizu, Wataru, Horie, Minoru, Kamiya, Kaichiro, Furukawa, Tetsushi, Fukuda, Keiichi
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039759/
https://ncbi.nlm.nih.gov/pubmed/27677334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34198
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍