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Molecular basis of the interaction between gating modifier spider toxins and the voltage sensor of voltage-gated ion channels

Voltage-sensor domains (VSDs) are modular transmembrane domains of voltage-gated ion channels that respond to changes in membrane potential by undergoing conformational changes that are coupled to gating of the ion-conducting pore. Most spider-venom peptides function as gating modifiers by binding t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Lau, Carus H. Y., King, Glenn F., Mobli, Mehdi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039624/
https://ncbi.nlm.nih.gov/pubmed/27677715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34333
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