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Targeting sodium channel voltage sensors with spider toxins

Voltage-activated sodium (Nav) channels are essential in generating and propagating nerve impulses, placing them amongst the most widely targeted ion channels by toxins from venomous organisms. An increasing number of spider toxins have been shown to interfere with the voltage-driven activation proc...

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Detalhes bibliográficos
Main Authors: Bosmans, Frank, Swartz, Kenton J
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847040/
https://ncbi.nlm.nih.gov/pubmed/20097434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2009.12.007
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