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Targeting sodium channel voltage sensors with spider toxins

Voltage-activated sodium (Nav) channels are essential in generating and propagating nerve impulses, placing them amongst the most widely targeted ion channels by toxins from venomous organisms. An increasing number of spider toxins have been shown to interfere with the voltage-driven activation proc...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Bosmans, Frank, Swartz, Kenton J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847040/
https://ncbi.nlm.nih.gov/pubmed/20097434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2009.12.007
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