Schwann Cell O-GlcNAc Glycosylation Is Required for Myelin Maintenance and Axon Integrity

Schwann cells (SCs), ensheathing glia of the peripheral nervous system, support axonal survival and function. Abnormalities in SC metabolism affect their ability to provide this support and maintain axon integrity. To further interrogate this metabolic influence on axon–glial interactions, we genera...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Kim, Sungsu, Maynard, Jason C., Sasaki, Yo, Strickland, Amy, Sherman, Diane L., Brophy, Peter J., Burlingame, Alma L., Milbrandt, Jeffrey
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039245/
https://ncbi.nlm.nih.gov/pubmed/27629714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1235-16.2016
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