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Cytosolic N-GlcNAc proteins are formed by the action of endo-β-N-acetylglucosaminidase
NGLY1 is a widely conserved eukaryotic cytosolic deglycosylating enzyme involved in the endoplasmic reticulum-associated degradation (ERAD) process, which eliminates misfolded proteins through retrograde translocation and proteasomal degradation. A human genetic disorder called NGLY1-deficiency has...
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| Publicado no: | Biochem Biophys Res Commun |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7508226/ https://ncbi.nlm.nih.gov/pubmed/32782141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2020.06.127 |
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