4-isothiocyanate-2, 2, 6, 6-tetramethyl piperidinooxyl inhibits angiogenesis by suppressing VEGFR2 and Tie2 phosphorylation

Reactive oxygen species (ROS) are involved in the signaling pathway and are triggered by angiogenic factors, including vascular endothelial growth factor and angiopoietins. 4-isothiocyanate-2, 2, 6, 6-tetramethyl piperidinooxyl (4-ISO-Tempo) is one of the nitroxides that exhibits antioxidant activit...

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Vydáno v:Oncol Lett
Hlavní autoři: Liu, Yuanyuan, Gao, Jing, Huang, Shuangsheng, Hu, Lamei, Wang, Zhiqiang, Wang, Zheyuan, Chen, Xiao, Zhang, Xiaoyu, Li, Wenguang
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2016
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038461/
https://ncbi.nlm.nih.gov/pubmed/27698866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.4948
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