4-isothiocyanate-2, 2, 6, 6-tetramethyl piperidinooxyl inhibits angiogenesis by suppressing VEGFR2 and Tie2 phosphorylation

Reactive oxygen species (ROS) are involved in the signaling pathway and are triggered by angiogenic factors, including vascular endothelial growth factor and angiopoietins. 4-isothiocyanate-2, 2, 6, 6-tetramethyl piperidinooxyl (4-ISO-Tempo) is one of the nitroxides that exhibits antioxidant activit...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Liu, Yuanyuan, Gao, Jing, Huang, Shuangsheng, Hu, Lamei, Wang, Zhiqiang, Wang, Zheyuan, Chen, Xiao, Zhang, Xiaoyu, Li, Wenguang
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038461/
https://ncbi.nlm.nih.gov/pubmed/27698866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.4948
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