NF-κB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression

The transcription factor NF-κB is activated in a range of human cancers and is thought to promote tumorigenesis, mainly due to its ability to protect transformed cells from apoptosis. To investigate the role of NF-κB in epithelial plasticity and metastasis, we utilized a well-characterized in vitro/...

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Pubblicato in:J Clin Invest
Autori principali: Huber, Margit A., Azoitei, Ninel, Baumann, Bernd, Grünert, Stefan, Sommer, Andreas, Pehamberger, Hubert, Kraut, Norbert, Beug, Hartmut, Wirth, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2004
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Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC503772/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15314694/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI21358
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