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Evidence for defective energy homeostasis in amyotrophic lateral sclerosis: Benefit of a high-energy diet in a transgenic mouse model

Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease characterized by selective loss of motor neurons and progressive muscle wasting. Growing evidence indicates that mitochondrial dysfunction, not only occurring in motor neurons but also in skeletal muscle, may play a cruc...

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書誌詳細
主要な著者: Dupuis, Luc, Oudart, Hugues, René, Frédérique, de Aguilar, Jose-Luis Gonzalez, Loeffler, Jean-Philippe
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC503756/
https://ncbi.nlm.nih.gov/pubmed/15263088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402026101
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