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Genomic DNA double-strand breaks are targets for hepadnaviral DNA integration
Integrated hepadnaviral DNA in livers and tumors of chronic hepatitis B patients has been reported for many years. In this study, we investigated whether hepatitis B virus DNA integration occurs preferentially at sites of cell DNA damage. A single I-SceI homing endonuclease recognition site was intr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2004
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC503752/ https://ncbi.nlm.nih.gov/pubmed/15258290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403925101 |
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