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Genomic DNA double-strand breaks are targets for hepadnaviral DNA integration

Integrated hepadnaviral DNA in livers and tumors of chronic hepatitis B patients has been reported for many years. In this study, we investigated whether hepatitis B virus DNA integration occurs preferentially at sites of cell DNA damage. A single I-SceI homing endonuclease recognition site was intr...

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Hlavní autoři: Bill, Colin A., Summers, Jesse
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC503752/
https://ncbi.nlm.nih.gov/pubmed/15258290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403925101
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