Soluble adenylyl cyclase is essential for proper lysosomal acidification

Lysosomes, the degradative organelles of the endocytic and autophagic pathways, function at an acidic pH. Lysosomes are acidified by the proton-pumping vacuolar ATPase (V-ATPase), but the molecular processes that set the organelle’s pH are not completely understood. In particular, pH-sensitive signa...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Gen Physiol
Egile Nagusiak: Rahman, Nawreen, Ramos-Espiritu, Lavoisier, Milner, Teresa A., Buck, Jochen, Levin, Lonny R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2016
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037342/
https://ncbi.nlm.nih.gov/pubmed/27670898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201611606
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