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Soluble adenylyl cyclase is essential for proper lysosomal acidification
Lysosomes, the degradative organelles of the endocytic and autophagic pathways, function at an acidic pH. Lysosomes are acidified by the proton-pumping vacuolar ATPase (V-ATPase), but the molecular processes that set the organelle’s pH are not completely understood. In particular, pH-sensitive signa...
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| Publicado en: | J Gen Physiol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5037342/ https://ncbi.nlm.nih.gov/pubmed/27670898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201611606 |
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