Loading...

A point mutation in the regulatory light chain reduces the step size of skeletal muscle myosin

Current evidence favors the theory that, when the globular motor domain of myosin attaches to actin, the light chain binding domain or “lever arm” rotates, and thereby generates movement of actin filaments. Myosin is uniquely designed for such a role in that a long α-helix (≈9 nm) extending from the...

Full description

Saved in:
Bibliographic Details
Main Authors: Sherwood, Jennifer J., Waller, Guillermina S., Warshaw, David M., Lowey, Susan
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC503728/
https://ncbi.nlm.nih.gov/pubmed/15256600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401699101
Tags: Add Tag
No Tags, Be the first to tag this record!