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A point mutation in the regulatory light chain reduces the step size of skeletal muscle myosin

Current evidence favors the theory that, when the globular motor domain of myosin attaches to actin, the light chain binding domain or “lever arm” rotates, and thereby generates movement of actin filaments. Myosin is uniquely designed for such a role in that a long α-helix (≈9 nm) extending from the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sherwood, Jennifer J., Waller, Guillermina S., Warshaw, David M., Lowey, Susan
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC503728/
https://ncbi.nlm.nih.gov/pubmed/15256600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401699101
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