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Role of the Essential Light Chain in the Activation of Smooth Muscle Myosin by Regulatory Light Chain Phosphorylation

The activity of smooth and non-muscle myosin II is regulated by phosphorylation of the regulatory light chain (RLC) at serine 19. The dephosphorylated state of full-length monomeric myosin is characterized by an asymmetric intramolecular head-head interaction that completely inhibits the ATPase acti...

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Autors principals: Taylor, Kenneth A., Feig, Michael, Brooks, Charles L., Fagnant, Patricia M., Lowey, Susan, Trybus, Kathleen M.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065857/
https://ncbi.nlm.nih.gov/pubmed/24361582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2013.12.008
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