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A point mutation in the regulatory light chain reduces the step size of skeletal muscle myosin

Current evidence favors the theory that, when the globular motor domain of myosin attaches to actin, the light chain binding domain or “lever arm” rotates, and thereby generates movement of actin filaments. Myosin is uniquely designed for such a role in that a long α-helix (≈9 nm) extending from the...

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Bibliografski detalji
Glavni autori: Sherwood, Jennifer J., Waller, Guillermina S., Warshaw, David M., Lowey, Susan
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC503728/
https://ncbi.nlm.nih.gov/pubmed/15256600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401699101
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