Selective inhibition of the citrate-to-isocitrate reaction of cytosolic aconitase by phosphomimetic mutation of serine-711

Iron-regulatory protein 1 (IRP1) is a dual-function protein with mutually exclusive roles as a posttranscriptional regulator of animal-cell iron metabolism or as the cytosolic isoform of the iron–sulfur enzyme aconitase (c-acon). Much effort has focused on the role of IRP1 in posttranscriptional gen...

Full description

Saved in:
Bibliographic Details
Main Authors: Pitula, Joseph S., Deck, Kathryn M., Clarke, Stephen L., Anderson, Sheila A., Vasanthakumar, Aparna, Eisenstein, Richard S.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC503718/
https://ncbi.nlm.nih.gov/pubmed/15263083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404308101
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items