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Selective inhibition of the citrate-to-isocitrate reaction of cytosolic aconitase by phosphomimetic mutation of serine-711
Iron-regulatory protein 1 (IRP1) is a dual-function protein with mutually exclusive roles as a posttranscriptional regulator of animal-cell iron metabolism or as the cytosolic isoform of the iron–sulfur enzyme aconitase (c-acon). Much effort has focused on the role of IRP1 in posttranscriptional gen...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC503718/ https://ncbi.nlm.nih.gov/pubmed/15263083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404308101 |
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