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Gene Editing of Human Hematopoietic Stem and Progenitor Cells: Promise and Potential Hurdles

Hematopoietic stem and progenitor cells (HSPCs) have great therapeutic potential because of their ability to both self-renew and differentiate. It has been proposed that, given their unique properties, a small number of genetically modified HSPCs could accomplish lifelong, corrective reconstitution...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther
Main Authors: Yu, Kyung-Rok, Natanson, Hannah, Dunbar, Cynthia E.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035911/
https://ncbi.nlm.nih.gov/pubmed/27483988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2016.107
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