Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli

The degeneracy of the genetic code allows nucleic acids to encode amino acid identity as well as noncoding information for gene regulation and genome maintenance. The rare arginine codons AGA and AGG (AGR) present a case study in codon choice, with AGRs encoding important transcriptional and transla...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Napolitano, Michael G., Landon, Matthieu, Gregg, Christopher J., Lajoie, Marc J., Govindarajan, Lakshmi, Mosberg, Joshua A., Kuznetsov, Gleb, Goodman, Daniel B., Vargas-Rodriguez, Oscar, Isaacs, Farren J., Söll, Dieter, Church, George M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035903/
https://ncbi.nlm.nih.gov/pubmed/27601680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605856113
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