Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli

The degeneracy of the genetic code allows nucleic acids to encode amino acid identity as well as noncoding information for gene regulation and genome maintenance. The rare arginine codons AGA and AGG (AGR) present a case study in codon choice, with AGRs encoding important transcriptional and transla...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Napolitano, Michael G., Landon, Matthieu, Gregg, Christopher J., Lajoie, Marc J., Govindarajan, Lakshmi, Mosberg, Joshua A., Kuznetsov, Gleb, Goodman, Daniel B., Vargas-Rodriguez, Oscar, Isaacs, Farren J., Söll, Dieter, Church, George M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035903/
https://ncbi.nlm.nih.gov/pubmed/27601680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605856113
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