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Leptin promotes systemic lupus erythematosus by increasing autoantibody production and inhibiting immune regulation

Leptin is an adipocytokine that plays a key role in the modulation of immune responses and the development and maintenance of inflammation. Circulating levels of leptin are elevated in systemic lupus erythematosus (SLE) patients, but it is not clear whether this association can reflect a direct infl...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Lourenço, Elaine V., Liu, Aijing, Matarese, Giuseppe, La Cava, Antonio
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035847/
https://ncbi.nlm.nih.gov/pubmed/27588900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1607101113
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