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Mechanisms of Autoantibody Production in Systemic Lupus Erythematosus

Autoantibodies against a panoply of self-antigens are seen in systemic lupus erythematosus, but only a few (anti-Sm/RNP, anti-Ro/La, anti-dsDNA) are common. The common lupus autoantigens are nucleic acid complexes and levels of autoantibodies can be extraordinarily high. We explore why that is the c...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Han, Shuhong, Zhuang, Haoyang, Shumyak, Stepan, Yang, Lijun, Reeves, Westley H.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429614/
https://ncbi.nlm.nih.gov/pubmed/26029213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00228
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