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Leptin promotes systemic lupus erythematosus by increasing autoantibody production and inhibiting immune regulation

Leptin is an adipocytokine that plays a key role in the modulation of immune responses and the development and maintenance of inflammation. Circulating levels of leptin are elevated in systemic lupus erythematosus (SLE) patients, but it is not clear whether this association can reflect a direct infl...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Lourenço, Elaine V., Liu, Aijing, Matarese, Giuseppe, La Cava, Antonio
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035847/
https://ncbi.nlm.nih.gov/pubmed/27588900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1607101113
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