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Leptin promotes systemic lupus erythematosus by increasing autoantibody production and inhibiting immune regulation

Leptin is an adipocytokine that plays a key role in the modulation of immune responses and the development and maintenance of inflammation. Circulating levels of leptin are elevated in systemic lupus erythematosus (SLE) patients, but it is not clear whether this association can reflect a direct infl...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Lourenço, Elaine V., Liu, Aijing, Matarese, Giuseppe, La Cava, Antonio
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035847/
https://ncbi.nlm.nih.gov/pubmed/27588900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1607101113
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