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Leptin promotes systemic lupus erythematosus by increasing autoantibody production and inhibiting immune regulation

Leptin is an adipocytokine that plays a key role in the modulation of immune responses and the development and maintenance of inflammation. Circulating levels of leptin are elevated in systemic lupus erythematosus (SLE) patients, but it is not clear whether this association can reflect a direct infl...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lourenço, Elaine V., Liu, Aijing, Matarese, Giuseppe, La Cava, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035847/
https://ncbi.nlm.nih.gov/pubmed/27588900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1607101113
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