CRISPR/Cas9 Targeted Gene Editing and Cellular Engineering in Fanconi Anemia

The ability to rationally target disease-causing mutations has been made possible with programmable nucleases with the clustered, regularly interspaced short palindromic repeats/Cas9 system representing a facile platform for individualized gene-based medicine. In this study we employed footprint-fre...

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Detalles Bibliográficos
Publicado en:Stem Cells Dev
Autores principales: Osborn, Mark J., Lonetree, Cara-lin, Webber, Beau R., Patel, Dharmeshkumar, Dunmire, Samantha, DeFeo, Anthony P., McElroy, Amber N., MacMillan, Margaret L., Wagner, John E., Blazar, Bruce R., Tolar, Jakub
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Original Research Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035838/
https://ncbi.nlm.nih.gov/pubmed/27538887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2016.0149
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