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Enthalpy Screen of Drug Candidates
The enthalpic and entropic contributions to the binding affinity of drug candidates have been acknowledged to be important determinants of the quality of a drug molecule. These quantities, usually summarized in the thermodynamic signature, provide a rapid assessment of the forces that drive the bind...
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| 出版年: | Anal Biochem |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5035635/ https://ncbi.nlm.nih.gov/pubmed/27567994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2016.08.023 |
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