Genome-wide studies of von Willebrand Factor Propeptide Identify Loci Contributing to Variation in Propeptide Levels and von Willebrand Factor Clearance

BACKGROUND: Previous studies identified common variants at the ABO and VWF loci and unknown variants in a chromosome 2q12 linkage interval that contributed to the variation of plasma von Willebrand factor levels (VWF). While the association with ABO haplotypes can be explained by differential VWF cl...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Thromb Haemost
Prif Awduron: Ozel, A.B., McGee, B., Siemieniak, D., Jacobi, P.M., Haberichter, S.L., Brody, L.C., Mills, J.L., Molloy, A.M., Ginsburg, D., Li, J.Z., Desch, K.C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035595/
https://ncbi.nlm.nih.gov/pubmed/27359253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13401
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