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Von Willebrand Factor Propeptide to Antigen Ratio Identifies Platelet Activation and Reduced VWF Survival Phenotype in Mice

BACKGROUND: Reduced plasma survival of VWF is characteristic of patients with type 1C VWD. These subjects can be identified by an increased steady-state ratio of plasma VWFpp to VWF:Ag. A similar phenotype occurs in mice with the Mvwf1 allele. OBJECTIVES: To 1) determine if VWFpp/VWF:Ag ratio can be...

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Detalhes bibliográficos
Publicado no:J Thromb Haemost
Main Authors: Jacobi, Paula M., Kanaji, Sachiko, Jakab, David, Gehrand, Ashley L., Johnsen, Jill M., Haberichter, Sandra L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826853/
https://ncbi.nlm.nih.gov/pubmed/29285851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13934
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