Genome-wide studies of von Willebrand Factor Propeptide Identify Loci Contributing to Variation in Propeptide Levels and von Willebrand Factor Clearance

BACKGROUND: Previous studies identified common variants at the ABO and VWF loci and unknown variants in a chromosome 2q12 linkage interval that contributed to the variation of plasma von Willebrand factor levels (VWF). While the association with ABO haplotypes can be explained by differential VWF cl...

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Udgivet i:J Thromb Haemost
Main Authors: Ozel, A.B., McGee, B., Siemieniak, D., Jacobi, P.M., Haberichter, S.L., Brody, L.C., Mills, J.L., Molloy, A.M., Ginsburg, D., Li, J.Z., Desch, K.C.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035595/
https://ncbi.nlm.nih.gov/pubmed/27359253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13401
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