Preferential binding to dopamine D(3) over D(2) receptors by cariprazine in patients with schizophrenia using PET with the D(3)/D(2) receptor ligand [(11)C]-(+)-PHNO

RATIONALE: Second-generation antipsychotics occupy dopamine D(2) receptors and act as antagonists or partial agonists at these receptors. While these drugs alleviate positive symptoms in patients with schizophrenia, they are less effective for treating cognitive deficits and negative symptoms. Dopam...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Psychopharmacology (Berl)
मुख्य लेखकों: Girgis, Ragy R., Slifstein, Mark, D’Souza, Deepak, Lee, Yih, Periclou, Antonia, Ghahramani, Parviz, Laszlovszky, István, Durgam, Suresh, Adham, Nika, Nabulsi, Nabeel, Huang, Yiyun, Carson, Richard E., Kiss, Béla, Kapás, Margit, Abi-Dargham, Anissa, Rakhit, Ashok
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Springer Berlin Heidelberg 2016
विषय:
Original Investigation
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035321/
https://ncbi.nlm.nih.gov/pubmed/27525990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-016-4382-y
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