ANTIPSYCHOTIC BINDING TO THE DOPAMINE-3 RECEPTOR IN HUMANS: A PET STUDY WITH [11C]-(+)-PHNO

BACKGROUND: All currently available antipsychotic medications bind to both the dopamine-2 (D2) and dopamine-3 (D3) receptors in vitro. However, there is conflicting evidence from in vivo studies about whether or not antipsychotic medications bind to the D3 receptor (D3R). The purpose of this study w...

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Bibliographic Details
Published in:Schizophr Res
Main Authors: Girgis, Ragy R., Xu, Xiaoyan, Gil, Roberto B., Hackett, Elizabeth, Ojeil, Najate, Lieberman, Jeffrey A., Slifstein, Mark, Abi-Dargham, Anissa
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591174/
https://ncbi.nlm.nih.gov/pubmed/26190300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2015.06.027
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