Deficits in prefrontal cortical and extra-striatal dopamine release in schizophrenia: a PET fMRI study

IMPORTANCE: Multiple lines of evidence suggest a deficit in dopamine release in prefrontal cortex in schizophrenia. Despite the prevalence of the concept of prefrontal cortical hypodopaminergia in schizophrenia, in vivo imaging of dopamine release in prefrontal cortex has not been possible until rec...

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Publicado en:JAMA Psychiatry
Autores principales: Slifstein, Mark, van de Giessen, Elsmarieke, Van Snellenberg, Jared, Thompson, Judy L., Narendran, Rajesh, Gil, Roberto, Hackett, Elizabeth, Girgis, Ragy, Ojeil, Najate, Moore, Holly, D’Souza, Deepak, Malison, Robert T., Huang, Yiyun, Lim, Keun-poong, Nabulsi, Nabeel, Carson, Richard E., Lieberman, Jeffery A., Abi-Dargham, Anissa
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768742/
https://ncbi.nlm.nih.gov/pubmed/25651194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamapsychiatry.2014.2414
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