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Bempedoic Acid (ETC-1002): an Investigational Inhibitor of ATP Citrate Lyase

Bempedoic acid (ETC-1002), a novel therapeutic approach for low-density lipoprotein cholesterol (LDL-C) lowering, inhibits ATP citrate lyase (ACL), an enzyme involved in fatty acid and cholesterol synthesis. Although rodent studies suggested potential effects of ACL inhibition on both fatty acid and...

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Bibliografske podrobnosti
izdano v:Curr Atheroscler Rep
Main Authors: Bilen, Ozlem, Ballantyne, Christie M.
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035316/
https://ncbi.nlm.nih.gov/pubmed/27663902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11883-016-0611-4
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