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ATP-Citrate Lyase Deficiency in the Mouse
ATP-citrate lyase (Acly) is one of two cytosolic enzymes that synthesize acetyl-coenzyme A (CoA). Because acetyl-CoA is an essential building block for cholesterol and triglycerides, Acly has been considered a therapeutic target for hyperlipidemias and obesity. To define the phenotype of Acly-defici...
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| Huvudupphovsmän: | , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2003
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2888281/ https://ncbi.nlm.nih.gov/pubmed/14662765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M310512200 |
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