ATP-Citrate Lyase Deficiency in the Mouse

ATP-citrate lyase (Acly) is one of two cytosolic enzymes that synthesize acetyl-coenzyme A (CoA). Because acetyl-CoA is an essential building block for cholesterol and triglycerides, Acly has been considered a therapeutic target for hyperlipidemias and obesity. To define the phenotype of Acly-defici...

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Bibliografski detalji
Glavni autori: Beigneux, Anne P., Kosinski, Cynthia, Gavino, Bryant, Horton, Jay D., Skarnes, William C., Young, Stephen G.
Format: Artigo
Jezik:Inglês
Izdano: 2003
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888281/
https://ncbi.nlm.nih.gov/pubmed/14662765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M310512200
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