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ATP citrate lyase knockdown impacts cancer stem cells in vitro

ATP citrate lyase (ACL) knockdown (KD) causes tumor suppression and induces differentiation. We have previously reported that ACL KD reverses epithelial–mesenchymal transition (EMT) in lung cancer cells. Because EMT is often associated with processes that induce stemness, we hypothesized that ACL KD...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hanai, J-i, Doro, N, Seth, P, Sukhatme, V P
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702307/
https://ncbi.nlm.nih.gov/pubmed/23807225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.215
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