Chromosomal organization of the heavy chain variable region gene segments comprising the human fetal antibody repertoire.

The adult repertoire of antibody specificities is acquired in a developmentally programmed fashion that, in mouse and man, parallels the ordered rearrangement of a limited number of germ-line heavy chain variable region (VH) gene segments during development. It has been hypothesized that this develo...

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Bibliographic Details
Main Authors: Willems van Dijk, K, Milner, L A, Sasso, E H, Milner, E C
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC50352/
https://ncbi.nlm.nih.gov/pubmed/1438230
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