EKLF/KLF1-regulated cell cycle exit is essential for erythroblast enucleation

The mechanisms regulating the sequential steps of terminal erythroid differentiation remain largely undefined, yet are relevant to human anemias that are characterized by ineffective red cell production. Erythroid Krüppel-like Factor (EKLF/KLF1) is a master transcriptional regulator of erythropoiesi...

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Vydáno v:Blood
Hlavní autoři: Gnanapragasam, Merlin Nithya, McGrath, Kathleen E., Catherman, Seana, Xue, Li, Palis, James, Bieker, James J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2016
Témata:
Red Cells, Iron, and Erythropoiesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034741/
https://ncbi.nlm.nih.gov/pubmed/27480112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-03-706671
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