EKLF/KLF1-regulated cell cycle exit is essential for erythroblast enucleation

The mechanisms regulating the sequential steps of terminal erythroid differentiation remain largely undefined, yet are relevant to human anemias that are characterized by ineffective red cell production. Erythroid Krüppel-like Factor (EKLF/KLF1) is a master transcriptional regulator of erythropoiesi...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Gnanapragasam, Merlin Nithya, McGrath, Kathleen E., Catherman, Seana, Xue, Li, Palis, James, Bieker, James J.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2016
Matèries:
Red Cells, Iron, and Erythropoiesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034741/
https://ncbi.nlm.nih.gov/pubmed/27480112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-03-706671
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