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EKLF/KLF1-regulated cell cycle exit is essential for erythroblast enucleation

The mechanisms regulating the sequential steps of terminal erythroid differentiation remain largely undefined, yet are relevant to human anemias that are characterized by ineffective red cell production. Erythroid Krüppel-like Factor (EKLF/KLF1) is a master transcriptional regulator of erythropoiesi...

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Détails bibliographiques
Publié dans:Blood
Auteurs principaux: Gnanapragasam, Merlin Nithya, McGrath, Kathleen E., Catherman, Seana, Xue, Li, Palis, James, Bieker, James J.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034741/
https://ncbi.nlm.nih.gov/pubmed/27480112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-03-706671
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