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EKLF/KLF1-regulated cell cycle exit is essential for erythroblast enucleation

The mechanisms regulating the sequential steps of terminal erythroid differentiation remain largely undefined, yet are relevant to human anemias that are characterized by ineffective red cell production. Erythroid Krüppel-like Factor (EKLF/KLF1) is a master transcriptional regulator of erythropoiesi...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Gnanapragasam, Merlin Nithya, McGrath, Kathleen E., Catherman, Seana, Xue, Li, Palis, James, Bieker, James J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034741/
https://ncbi.nlm.nih.gov/pubmed/27480112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-03-706671
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