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Immature erythroblasts with extensive ex vivo self-renewal capacity emerge from the early mammalian fetus

In the hematopoietic hierarchy, only stem cells are thought to be capable of long-term self-renewal. Erythroid progenitors derived from fetal or adult mammalian hematopoietic tissues are capable of short-term, or restricted (10(2)- to 10(5)-fold), ex vivo expansion in the presence of erythropoietin,...

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Detalhes bibliográficos
Main Authors: England, Samantha J., McGrath, Kathleen E., Frame, Jenna M., Palis, James
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062358/
https://ncbi.nlm.nih.gov/pubmed/21127173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-07-299743
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