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EKLF/KLF1-regulated cell cycle exit is essential for erythroblast enucleation

The mechanisms regulating the sequential steps of terminal erythroid differentiation remain largely undefined, yet are relevant to human anemias that are characterized by ineffective red cell production. Erythroid Krüppel-like Factor (EKLF/KLF1) is a master transcriptional regulator of erythropoiesi...

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Bibliografiske detaljer
Udgivet i:Blood
Main Authors: Gnanapragasam, Merlin Nithya, McGrath, Kathleen E., Catherman, Seana, Xue, Li, Palis, James, Bieker, James J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034741/
https://ncbi.nlm.nih.gov/pubmed/27480112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-03-706671
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