Effects of Ketamine and Ketamine Metabolites on Evoked Striatal Dopamine Release, Dopamine Receptors, and Monoamine Transporters

Following administration at subanesthetic doses, (R,S)-ketamine (ketamine) induces rapid and robust relief from symptoms of depression in treatment-refractory depressed patients. Previous studies suggest that ketamine’s antidepressant properties involve enhancement of dopamine (DA) neurotransmission...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Can, Adem, Zanos, Panos, Moaddel, Ruin, Kang, Hye Jin, Dossou, Katinia S. S., Wainer, Irving W., Cheer, Joseph F., Frost, Douglas O., Huang, Xi-Ping, Gould, Todd D.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2016
Assuntos:
Neuropharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034706/
https://ncbi.nlm.nih.gov/pubmed/27469513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.235838
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