The regulator of G-protein signaling RGS16 promotes insulin secretion and β-cell proliferation in rodent and human islets

OBJECTIVE: G protein-coupled receptor (GPCR) signaling regulates insulin secretion and pancreatic β cell-proliferation. While much knowledge has been gained regarding how GPCRs are activated in β cells, less is known about the mechanisms controlling their deactivation. In many cell types, terminatio...

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Publicat a:Mol Metab
Autors principals: Vivot, Kevin, Moullé, Valentine S., Zarrouki, Bader, Tremblay, Caroline, Mancini, Arturo D., Maachi, Hasna, Ghislain, Julien, Poitout, Vincent
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034687/
https://ncbi.nlm.nih.gov/pubmed/27689011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.08.010
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