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Pronounced proliferation of non-beta cells in response to beta-cell mitogens in isolated human islets of Langerhans

The potential to treat diabetes by increasing beta-cell mass is driving a major effort to identify beta-cell mitogens. Demonstration of mitogen activity in human beta cells is frequently performed in ex vivo assays. However, reported disparities in the efficacy of beta-cell mitogens led us to invest...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Maachi, Hasna, Ghislain, Julien, Tremblay, Caroline, Poitout, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8163757/
https://ncbi.nlm.nih.gov/pubmed/34050242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90643-3
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