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The Nuclear Protein IκBζ Forms a Transcriptionally Active Complex with Nuclear Factor-κB (NF-κB) p50 and the Lcn2 Promoter via the N- and C-terminal Ankyrin Repeat Motifs

The nuclear protein IκBζ, comprising the N-terminal trans-activation domain and the C-terminal ankyrin repeat (ANK) domain composed of seven ANK motifs, activates transcription of a subset of nuclear factor-κB (NF-κB)-dependent innate immune genes such as Lcn2 encoding the antibacterial protein lipo...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kohda, Akira, Yamazaki, Soh, Sumimoto, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034063/
https://ncbi.nlm.nih.gov/pubmed/27489104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.719302
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