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Nuclear Localization of IκBα Is Mediated by the Second Ankyrin Repeat: the IκBα Ankyrin Repeats Define a Novel Class of cis-Acting Nuclear Import Sequences

The ability of the IκBα protein to sequester dimeric NF-κB/Rel proteins in the cytoplasm provides an effective mechanism for regulating the potent transcriptional activation properties of NF-κB/Rel family members. IκBα can also act in the nucleus as a postinduction repressor of NF-κB/Rel proteins. T...

詳細記述

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書誌詳細
主要な著者: Sachdev, Shrikesh, Hoffmann, Alexander, Hannink, Mark
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC110632/
https://ncbi.nlm.nih.gov/pubmed/9566872
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