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Nuclear Localization of IκBα Is Mediated by the Second Ankyrin Repeat: the IκBα Ankyrin Repeats Define a Novel Class of cis-Acting Nuclear Import Sequences

The ability of the IκBα protein to sequester dimeric NF-κB/Rel proteins in the cytoplasm provides an effective mechanism for regulating the potent transcriptional activation properties of NF-κB/Rel family members. IκBα can also act in the nucleus as a postinduction repressor of NF-κB/Rel proteins. T...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sachdev, Shrikesh, Hoffmann, Alexander, Hannink, Mark
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 1998
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC110632/
https://ncbi.nlm.nih.gov/pubmed/9566872
Tagiau: Ychwanegu Tag
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