Nuclear Localization of IκBα Is Mediated by the Second Ankyrin Repeat: the IκBα Ankyrin Repeats Define a Novel Class of cis-Acting Nuclear Import Sequences
The ability of the IκBα protein to sequester dimeric NF-κB/Rel proteins in the cytoplasm provides an effective mechanism for regulating the potent transcriptional activation properties of NF-κB/Rel family members. IκBα can also act in the nucleus as a postinduction repressor of NF-κB/Rel proteins. T...
שמור ב:
| הוצא לאור ב: | Mol Cell Biol |
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| Principais autores: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Taylor & Francis
1998
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110632/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9566872/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.5.2524 |
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