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Divergent effects of Porcupine and Wntless on WNT1 trafficking, secretion, and signaling

Loss-of-function studies have identified Porcupine (PORCN) and Wntless (WLS) as essential mediators of Wnt secretion and signaling. Whereas PORCN is thought to palmitoylate Wnt proteins, WLS is believed to transport palmitoylated Wnt proteins to the cell surface. However, little is known about how t...

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書目詳細資料
發表在:Exp Cell Res
Main Authors: Galli, Lisa M., Zebarjadi, Navid, Li, Lydia, Lingappa, Vishwanath R., Burrus, Laura W.
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5032901/
https://ncbi.nlm.nih.gov/pubmed/27492485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2016.07.028
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