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Divergent effects of Porcupine and Wntless on WNT1 trafficking, secretion, and signaling
Loss-of-function studies have identified Porcupine (PORCN) and Wntless (WLS) as essential mediators of Wnt secretion and signaling. Whereas PORCN is thought to palmitoylate Wnt proteins, WLS is believed to transport palmitoylated Wnt proteins to the cell surface. However, little is known about how t...
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| Publicado no: | Exp Cell Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5032901/ https://ncbi.nlm.nih.gov/pubmed/27492485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2016.07.028 |
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